MetroDIS is staffed by rotating drug information pharmacists with broad pharmacy and health care knowledge, and literature searching skills. MetroDIS is supported by Sunnybrook pharmacy's Medication Information, Safety and Quality (MedIQS) team.

Other Sunnybrook pharmacists, including those working in critical care, cardiology, infectious disease, nephrology, oncology and neontal care may be consulted for their specialized expertise, where appropriate.